SCHEMBL146018

SCHEMBL146018

O=C(Cc1ccccc1)c1ccc(O)cc1O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.80
ESR2 Q92731 2/20 0.80
SHBG P04278 1/20 0.80
RAB9A P51151 4/20 0.71
LMNA P02545 3/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
NPC1 O15118 3/20 0.71
MAPT P10636 3/20 0.71
GAA P10253 2/20 0.71
HTT P42858 1/20 0.71
ALOX12 P18054 1/20 0.71
ALOX5 P09917 1/20 0.69
ALDH1A1 P00352 3/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
CYP3A4 P08684 1/20 0.65
HPGD P15428 1/20 0.65
ATM Q13315 1/20 0.65
MAPK1 P28482 1/20 0.62
HSP90AB1 P08238 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497946 1.00 ESR1 (0.80) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL312243 0.89 ESR1 (1.00) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL30503014 0.89 ESR1 (1.00) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL14855982 0.88 ESR1 (0.72) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL9061935 0.86 ESR1 (0.59) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL2331960 0.85 ESR1 (0.78) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL3586687 0.83 ESR1 (0.81) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL22672221 0.83 ESR1 (0.81) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL11517499 0.83 LMNA (0.60) ESR1ESR2SHBGRAB9ALMNA
SCHEMBL3958571 0.83 LMNA (1.00) ESR1ESR2SHBGRAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862072-A1 COMPOSITION USEFUL FOR PRODUCTION OF ACIDIC GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2021-08-11 EP claimed
CN-112888498-A Composition useful for producing acid gas separation membranes 住友化学株式会社 2021-06-01 CN claimed
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP claimed
WO-2020071411-A1 COMPOSITION USEFUL FOR PRODUCTION OF ACIDIC GAS SEPARATION MEMBRANE 住友化学株式会社 2020-04-09 WO claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
EP-2613819-B1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2018-01-10 EP claimed
EP-2114847-B1 METHOD FOR THE PRODUCTION OF 2,4-DIHYDROXYPHENYL-BENZYL KETONES PLANT HEALTH CARE INC (US) 2017-03-22 EP claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
CN-103209717-B Lubricious coatings for medical devices BIOINTERACTIONS LTD 2015-04-08 CN claimed
CN-104345550-A Colored photosensitive resin composition, color filter, and liquid crystal display device having the same DONGWOO FINE CHEM CO LTD 2015-02-11 CN claimed
US-8541498-B2 Lubricious coatings for medical devices BIOINTERACTIONS LTD. (GB) 2013-09-24 US claimed
EP-2613819-A1 Lubricious coatings for medical devices Biointeractions Ltd. (GB) 2013-07-17 EP claimed
WO-2012032283-A1 Lubricious coatings for medical devices BIOINTERACTIONS LTD (GB) 2012-03-15 WO claimed
US-20120059111-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD. (GB) 2012-03-08 US claimed
EP-0941992-B1 Ipriflavone preparation process ERREGIERRE SPA (IT) 2002-05-08 EP claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US claimed
US-5973169-A Ipriflavone preparation process ERREGIERRE S.P.A. (IT) 1999-10-26 US claimed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP claimed
JP-9052860-A None JP disclosed
US-4163746-A ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-08-07 US disclosed