Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517533 | 0.85 | PRSS1 (0.60) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL8241799 | 0.84 | CACNA1H (0.56) | PRSS1TPSAB1ALDH1A1CACNA1HABCB1 | |
| SCHEMBL7505433 | 0.84 | PRSS1 (0.59) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL316882 | 0.84 | ALDH1A1 (0.55) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| SCHEMBL25461074 | 0.83 | ABCB1 (0.55) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| SCHEMBL25380156 | 0.83 | PRSS1 (0.57) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL6447135 | 0.83 | ALDH1A1 (0.53) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL6444517 | 0.83 | ALDH1A1 (0.53) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| SCHEMBL2621484 | 0.83 | ALDH1A1 (0.58) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| SCHEMBL8555208 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDABCB1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504431-B2 | Sulfonyl amide inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-03-17 | — | — | US | disclosed |
| US-20050245535-A1 | Sulfonyl amide inhibitors of calcium channel function | BRISTOL- MYERS SQUIBB COMPANY | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245535-A1 | Sulfonyl amide inhibitors of calcium channel function | CACNA1F, CACNA1A, CACNA1D | PRSS1 2023/4885TPSAB1 2512/4885ALDH1A1 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.