Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517299 | 1.00 | KMT2A (0.34) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11516820 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11507044 | 0.83 | KMT2A (0.35) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11506505 | 0.83 | KMT2A (0.35) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11506506 | 0.83 | KMT2A (0.35) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11520696 | 0.82 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11446751 | 0.79 | SMN1; SMN2 (0.38) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11518232 | 0.77 | KDM4E (0.38) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11521080 | 0.77 | KDM4E (0.38) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11443828 | 0.75 | SMN1; SMN2 (0.35) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |