SCHEMBL11517853

SCHEMBL11517853

COc1ccc2nc3ccc(Cl)cc3cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 2/20 0.52
POLB P06746 2/20 0.52
MEN1 O00255 1/20 0.52
NPC1 O15118 1/20 0.52
LMNA P02545 1/20 0.52
NQO2 P16083 1/20 0.52
RAB9A P51151 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NCF1 P14598 1/20 0.51
NQO1 P15559 1/20 0.49
MAPT P10636 3/20 0.48
FLT3 P36888 1/20 0.48
AMY1A P0DUB6 1/20 0.47
PDE3B Q13370 1/20 0.46
PDE3A Q14432 1/20 0.46
EGFR P00533 1/20 0.46
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278565 0.91 NCF1 (0.56) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL30227262 0.91 NCF1 (0.56) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL31414248 0.88 KDM4E (0.63) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL7694434 0.84 CYP2A6 (0.60) KDM4ERAB9ANCF1FLT3
SCHEMBL11442590 0.83 ALDH1A1 (0.69) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL12068392 0.81 ALDH1A1 (0.57) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL8749477 0.80 CYP2A6 (0.61) KDM4ERAB9AFLT3
SCHEMBL27918947 0.80 PDGFRB (0.58) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL1527016 0.79 ALDH1A1 (0.69) KDM4EALDH1A1POLBMEN1NPC1
SCHEMBL30065110 0.79 ALDH1A1 (0.69) KDM4EALDH1A1POLBMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed