SCHEMBL278565

SCHEMBL278565

COc1ccc2nc3cc(Cl)ccc3cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.56
NQO1 P15559 1/20 0.53
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 3/20 0.49
GFER P55789 1/20 0.49
MAPT P10636 1/20 0.48
KMT2A Q03164 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
NQO2 P16083 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
AMY1A P0DUB6 1/20 0.44
ADORA2A P29274 1/20 0.43
PHLPP2 Q6ZVD8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30227262 1.00 NCF1 (0.56) NCF1NQO1KDM4EALDH1A1GFER
SCHEMBL11517853 0.91 KDM4E (0.52) NCF1NQO1KDM4EALDH1A1MAPT
SCHEMBL12068392 0.91 ALDH1A1 (0.57) NCF1NQO1KDM4EALDH1A1GFER
SCHEMBL31414248 0.84 KDM4E (0.63) NCF1NQO1KDM4EALDH1A1MAPT
SCHEMBL11442590 0.82 ALDH1A1 (0.69) KDM4EALDH1A1GFERMAPTKMT2A
SCHEMBL18809011 0.81 NCF1 (0.57) NCF1NQO1KDM4EALDH1A1MAPT
SCHEMBL12068387 0.80 NCF1 (0.56) NCF1NQO1KDM4EALDH1A1KMT2A
SCHEMBL3364517 0.80 NCF1 (0.65) NCF1NQO1KDM4EALDH1A1KMT2A
SCHEMBL7694434 0.80 CYP2A6 (0.60) NCF1KDM4ERAB9ACYP1A2CYP2A6
SCHEMBL12068383 0.79 KDM4E (0.50) KDM4EALDH1A1MAPTNQO2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137806-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2026-05-21 US claimed
WO-2023225631-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2023-11-23 WO claimed
EP-3484908-A1 NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS AM Chemicals Llc (US) 2019-05-22 EP claimed
US-20180016232-A1 SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES AM CHEMICALS LLC (US) 2018-01-18 US claimed
WO-2018013999-A1 NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC (US) 2018-01-18 WO claimed
US-20090307805-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V 2009-12-10 US claimed
EP-1974053-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE Keygene N.V. (NL) 2008-10-01 EP claimed
WO-2007073149-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V. (NL) 2007-06-28 WO claimed
WO-2007073154-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V. (NL) 2007-06-28 WO claimed
EP-0163316-B1 PLATINUM-INTERCALATIVE COMPLEXES FOR THE TREATMENT OF CANCER MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-05-16 EP claimed
EP-0163316-A1 Platinum-intercalative complexes for the treatment of cancer MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1985-12-04 EP claimed
US-20260137806-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2026-05-21 US disclosed
EP-4525855-A1 INTERCALATING SUGAR MOLECULES Xalud Therapeutics, Inc. (US) 2025-03-26 EP disclosed
US-20230407316-A1 COMPOSITIONS AND METHODS FOR HIGH FIDELITY ASSEMBLY OF NUCLEIC ACIDS GEN9, INC. (US) 2023-12-21 US disclosed
WO-2023225631-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2023-11-23 WO disclosed
WO-1993020074-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR ACRIDINE-9-CARBOXYLIC ACIDS ABBOTT LABORATORIES (US) 1993-10-14 WO disclosed
EP-0240914-B1 PEPTIDE DERIVATIVES AND ACTIVITY MEASURING METHOD OF PHYSIOLOGICALLY ACTIVE SUBSTANCES USING THE SAME AS SUBSTRATES WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-19 EP disclosed
EP-0163316-B1 PLATINUM-INTERCALATIVE COMPLEXES FOR THE TREATMENT OF CANCER MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-05-16 EP disclosed
US-4843161-A Platinum-intercalative complexes for the treatment of cancer MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-06-27 US disclosed
EP-0163316-A1 Platinum-intercalative complexes for the treatment of cancer MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1985-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137806-A1 INTERCALATING SUGAR MOLECULES SLC2A1, SLC2A2, SLC2A4 NCF1 1569/4885NQO1 914/4885KDM4E 3652/4885
US-20180016232-A1 SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES NCL, PAICS, RTCB NCF1 586/4885NQO1 2753/4885KDM4E 4024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.