Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 5/20 | 0.42 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519144 | 0.88 | FKBP5 (0.44) | ACERENFKBP5ACE2PREP | |
| SCHEMBL11435667 | 0.83 | ACE (0.55) | ACERENACE2MEN1FAAH | |
| SCHEMBL18374218 | 0.83 | ACE (0.45) | NPSR1ACEPRCPACE2MEN1 | |
| SCHEMBL11516346 | 0.83 | FKBP5 (0.44) | ACERENFKBP5ACE2PREP | |
| SCHEMBL11429550 | 0.82 | NPSR1 (0.52) | NPSR1ACERENFKBP5PRCP | |
| SCHEMBL11517747 | 0.81 | FKBP5 (0.43) | ACERENFKBP5ACE2PREP | |
| SCHEMBL8615903 | 0.81 | XIAP (0.48) | XIAP | |
| SCHEMBL8920639 | 0.81 | XIAP (0.48) | XIAP | |
| SCHEMBL11517692 | 0.81 | FKBP5 (0.47) | NPSR1ACERENFKBP5PREP | |
| SCHEMBL10954689 | 0.81 | XIAP (0.46) | ACERENFKBP5ACE2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | claimed |
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | disclosed |