Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519144 | 0.85 | FKBP5 (0.44) | FKBP5POLBKMT2AACEREN | |
| SCHEMBL11516346 | 0.85 | FKBP5 (0.44) | FKBP5ACERENPREPFAP | |
| SCHEMBL11517747 | 0.84 | FKBP5 (0.43) | FKBP5POLBKMT2AACEREN | |
| SCHEMBL10954689 | 0.82 | XIAP (0.46) | FKBP5ACERENPREPFAP | |
| SCHEMBL11518286 | 0.81 | ACE (0.44) | FKBP5POLBACERENTSHR | |
| SCHEMBL11518459 | 0.81 | NPSR1 (0.47) | FKBP5NPSR1KMT2AACEREN | |
| SCHEMBL11517312 | 0.78 | PREP (0.62) | ACEPREPFAP | |
| SCHEMBL11516789 | 0.78 | ITGB1 (0.50) | FKBP5POLB | |
| Bromide SCHEMBL11515540 | 0.78 | DPP4 (0.49) | FKBP5ACERENPREPFAP | |
| SCHEMBL3279377 | 0.76 | P2RX7 (0.51) | FKBP5NPSR1POLBCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | claimed |
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | disclosed |