Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658104 | 0.81 | DRD1 (0.37) | MAOAMAOBCYP2C9ATMMEN1 | |
| SCHEMBL14476649 | 0.76 | GPR3 (0.38) | ATMMEN1KMT2AMAPTHDAC3 | |
| SCHEMBL29162234 | 0.74 | MAOA (0.52) | MAOAMAOBCYP2C9ATMMEN1 | |
| SCHEMBL6369839 | 0.72 | HTR2A (0.42) | MEN1KMT2ALMNAMAPTHTR2A | |
| SCHEMBL14591618 | 0.71 | RET (0.44) | MAOAMAOBHTR2ATSHRNPSR1 | |
| SCHEMBL19611588 | 0.69 | MAOA (0.47) | MAOAMAOBCYP2C9ATMMEN1 | |
| SCHEMBL29162236 | 0.69 | MAOA (0.47) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL19458502 | 0.69 | MAOA (0.64) | MAOAMAOBCYP2C9ATMMEN1 | |
| SCHEMBL16835547 | 0.67 | MAOA (0.61) | MAOAMAOBCYP2C9ATMMEN1 | |
| SCHEMBL29056534 | 0.67 | MAOA (0.61) | MAOAMAOBCYP2C9ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125926-A | Dimethylaminoethoxy ethanol methyl synthesis process and system | 安徽恒光聚氨酯材料有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-116802187-A | Organometallic compounds | 优米科尔股份公司及两合公司 | 2023-09-22 | — | — | CN | claimed |
| CN-111099941-A | Preparation method of alkyl nitrile compound | 中国科学院上海有机化学研究所 | 2020-05-05 | — | — | CN | claimed |
| CN-108623495-A | A kind of preparation method of aromatic nitriles or miscellaneous aromatic nitrile compounds | 中国科学院上海有机化学研究所 | 2018-10-09 | — | — | CN | claimed |
| CN-105601495-B | It is a kind of how the synthetic method of the smooth intermediate of appropriate pyrrole | 合肥利夫生物科技有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-105541594-B | It is a kind of how the synthetic method of the smooth intermediate 2 of appropriate pyrrole (3,5 bis trifluoromethyl phenyl) 2 methylpropanoic acids | 合肥利夫生物科技有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-103228612-B | With the method that primary alconol homogeneous catalysis high selectivity direct aminatin is primary amine by high liquid/vapor volume ratio and/or high pressure ammonia | EVONIK DEGUSSA GMBH (DE) | 2016-03-23 | — | — | CN | claimed |
| CN-101973911-B | Method for synthesizing anastrozole intermediate-2,2'-(5-methyl-1,3-phenylene)-bis-(2-methyl propionitrile) | USTC UNIV SCIENCE TECH CN | 2013-11-06 | — | — | CN | claimed |
| CN-102001933-B | Method for synthesizing naproxen | USTC UNIV SCIENCE TECH CN | 2013-07-17 | — | — | CN | claimed |
| CN-101973869-B | Method for synthesis of flurbiprofen | USTC UNIV SCIENCE TECH CN | 2013-05-29 | — | — | CN | claimed |
| CN-102285887-A | Method for preparing nitro-substituted diphenylmethane and derivative thereof | — | 2011-12-21 | — | — | CN | claimed |
| CN-102010317-A | Method for synthesizing felbinac and derivatives thereof | USTC UNIV SCIENCE TECH CN | 2011-04-13 | — | — | CN | claimed |
| CN-102010323-A | Method for synthesizing ibuprofen and analogues thereof | USTC UNIV SCIENCE TECH CN | 2011-04-13 | — | — | CN | claimed |
| CN-102001933-A | Method for synthesizing naproxen | USTC UNIV SCIENCE TECH CN | 2011-04-06 | — | — | CN | claimed |
| CN-101973869-A | Method for synthesis of flurbiprofen | USTC UNIV SCIENCE TECH CN | 2011-02-16 | — | — | CN | claimed |
| CN-101973911-A | Method for synthesizing anastrozole intermediate-2,2'-(5-methyl-1,3-phenylene)-bis-(2-methyl propionitrile) | USTC UNIV SCIENCE TECH CN | 2011-02-16 | — | — | CN | claimed |
| CN-101863826-A | Method for preparing 2-benzyl pyridine compound | USTC UNIV SCIENCE TECH CN | 2010-10-20 | — | — | CN | claimed |
| CN-101253144-A | Process for preparing aniline | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-27 | — | — | CN | claimed |
| CN-1196664-C | hydroformylation of allyl alcohol | ARCO CHEM TECH (US) | 2005-04-13 | — | — | CN | claimed |
| CN-1394197-A | hydroformylation of allyl alcohol | ARCO CHEM TECH (US) | 2003-01-29 | — | — | CN | claimed |