Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545663 | 0.77 | GPR3 (0.41) | ATMMEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL29162234 | 0.77 | MAOA (0.52) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL2834111 | 0.72 | MAOA (0.52) | MAOAMAOBPKMNR3C1ATM | |
| SCHEMBL29162236 | 0.72 | MAOA (0.47) | MAOAMAOBPKMATMMEN1 | |
| SCHEMBL115188 | 0.69 | MAOA (0.48) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL29797921 | 0.69 | MAOA (0.58) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL436702 | 0.69 | MAOA (0.58) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL19458502 | 0.68 | MAOA (0.64) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL16835547 | 0.66 | MAOA (0.61) | MAOAMAOBATMMEN1KMT2A | |
| SCHEMBL29056534 | 0.66 | MAOA (0.61) | MAOAMAOBATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460762-A | Polymer for electronic device | 杜邦电子公司 | 2024-01-26 | — | — | CN | claimed |
| CN-105523916-B | Synthesis how the method for appropriate pyrrole smooth intermediate impurities 2- (3,5- bis trifluoromethyl phenyl) propionic acid | 中国科学技术大学先进技术研究院 | 2019-03-19 | — | — | CN | claimed |
| CN-105601495-B | It is a kind of how the synthetic method of the smooth intermediate of appropriate pyrrole | 合肥利夫生物科技有限公司 | 2018-05-29 | — | — | CN | claimed |
| US-20170334854-A1 | One-Step Process For The Synthesis Of Alkylated Metyrapone Analogs | W. R. GRACE & CO.-CONN. | 2017-11-23 | — | — | US | claimed |
| CN-105541593-B | A kind of synthetic method of pharmaceutical intermediate | 合肥利夫生物科技有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-105541594-B | It is a kind of how the synthetic method of the smooth intermediate 2 of appropriate pyrrole (3,5 bis trifluoromethyl phenyl) 2 methylpropanoic acids | 合肥利夫生物科技有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-101973911-B | Method for synthesizing anastrozole intermediate-2,2'-(5-methyl-1,3-phenylene)-bis-(2-methyl propionitrile) | USTC UNIV SCIENCE TECH CN | 2013-11-06 | — | — | CN | claimed |
| CN-102001933-B | Method for synthesizing naproxen | USTC UNIV SCIENCE TECH CN | 2013-07-17 | — | — | CN | claimed |
| CN-102010323-B | Method for synthesizing ibuprofen and analogues thereof | USTC UNIV SCIENCE TECH CN | 2013-02-13 | — | — | CN | claimed |
| CN-102603527-A | Preparation method of functionalized aryl acetate compound | USTC UNIV SCIENCE TECH CN | 2012-07-25 | — | — | CN | claimed |
| CN-102452867-A | Method for preparing aryl acetonitrile compound | USTC UNIV SCIENCE TECH CN | 2012-05-16 | — | — | CN | claimed |
| CN-102285887-A | Method for preparing nitro-substituted diphenylmethane and derivative thereof | — | 2011-12-21 | — | — | CN | claimed |
| CN-102010323-A | Method for synthesizing ibuprofen and analogues thereof | USTC UNIV SCIENCE TECH CN | 2011-04-13 | — | — | CN | claimed |
| CN-102010317-A | Method for synthesizing felbinac and derivatives thereof | USTC UNIV SCIENCE TECH CN | 2011-04-13 | — | — | CN | claimed |
| CN-102001933-A | Method for synthesizing naproxen | USTC UNIV SCIENCE TECH CN | 2011-04-06 | — | — | CN | claimed |
| CN-101973911-A | Method for synthesizing anastrozole intermediate-2,2'-(5-methyl-1,3-phenylene)-bis-(2-methyl propionitrile) | USTC UNIV SCIENCE TECH CN | 2011-02-16 | — | — | CN | claimed |
| CN-101973869-A | Method for synthesis of flurbiprofen | USTC UNIV SCIENCE TECH CN | 2011-02-16 | — | — | CN | claimed |
| CN-101863826-A | Method for preparing 2-benzyl pyridine compound | USTC UNIV SCIENCE TECH CN | 2010-10-20 | — | — | CN | claimed |
| CN-117460762-A | Polymer for electronic device | 杜邦电子公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-101863826-A | Method for preparing 2-benzyl pyridine compound | USTC UNIV SCIENCE TECH CN | 2010-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334854-A1 | One-Step Process For The Synthesis Of Alkylated Metyrapone Analogs | MET, MEP1B, ABL1 | MAOA 720/4885MAOB 461/4885PKM 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.