Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MITF | O75030 | 3/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RNF4 | P78317 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155782 | 0.98 | PRMT1 (0.77) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL22931130 | 0.93 | PRMT1 (0.70) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL10996832 | 0.85 | PRMT1 (1.00) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL8047403 | 0.84 | PRMT1 (0.77) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL10574745 | 0.83 | PRMT1 (0.61) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL9081388 | 0.82 | NPC1 (0.76) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL11518539 | 0.82 | CA1 (0.53) | PRMT1MAPTKMT2AMEN1ATM | |
| Potassium Ion SCHEMBL11518837 | 0.82 | PRMT1 (0.74) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL7289377 | 0.82 | PRMT1 (0.74) | PRMT1NPC1RAB9AMITFNOD2 | |
| SCHEMBL7440868 | 0.82 | PRMT1 (0.74) | PRMT1MAPTKMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178301-A | 4-(2-(ACETYLTHIO)ACETAMIDO)BENZOIC ACID AS MUCOLYTIC AGENT | MEAD JOHNSON & COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4132802-A | LIQUEFACTION OF MUCUS | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4096277-A | Mucolytic mercaptoacylamidobenzamides and process of using same | MEAD JOHNSON & COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-4005222-A | Mucolytic mercaptoacylamidobenzoic and benzenesulfonic acid compounds and process | MEAD JOHNSON & COMPANY (US) | 1977-01-25 | — | — | US | disclosed |