SCHEMBL8047403

SCHEMBL8047403

O=C(CCl)Nc1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.77
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
MITF O75030 2/20 0.58
XBP1 P17861 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
NOD2 Q9HC29 1/20 0.58
ALDH1A1 P00352 5/20 0.56
HTT P42858 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAPT P10636 5/20 0.51
KMT2A Q03164 4/20 0.51
LMNA P02545 3/20 0.51
MEN1 O00255 3/20 0.51
KDM4E B2RXH2 2/20 0.51
ATM Q13315 1/20 0.51
RNF4 P78317 1/20 0.51
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10996832 0.87 PRMT1 (1.00) PRMT1NPC1RAB9AMITFXBP1
SCHEMBL14155782 0.85 PRMT1 (0.77) PRMT1NPC1RAB9AMITFXBP1
SCHEMBL9081388 0.84 NPC1 (0.76) PRMT1NPC1RAB9AMITFXBP1
SCHEMBL11518834 0.84 PRMT1 (0.74) PRMT1NPC1RAB9AMITFXBP1
SCHEMBL7440868 0.84 PRMT1 (0.74) PRMT1MAPTKMT2AMEN1CA1
SCHEMBL9623640 0.84 PRMT1 (0.54) PRMT1KMT2AMEN1ATMCA1
SCHEMBL30699954 0.84 PRMT1 (0.54) PRMT1KMT2AMEN1ATMCA1
Potassium Ion SCHEMBL11518837 0.84 PRMT1 (0.74) PRMT1NPC1RAB9AMITFXBP1
SCHEMBL7289377 0.84 PRMT1 (0.74) PRMT1NPC1RAB9AMITFXBP1
SCHEMBL1102000 0.84 ATM (0.74) PRMT1RAB9AALDH1A1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063541-A DOT-PROMOTING AGENTS IN PHOTOGRAPHY PROCESSED IN A STABLE DEVELOPER HAVING A PH<11 AND YIELD A HIGH-CONTRAST MATERIAL; IMPROVED SPEED, DEVELOPMENT RATE, LINE EDGE, DOT QUALITY AND SCREEN RANGE; REDUCED PEPPER GRAIN ON DEVELOPMENT KODAK POLYCHROME GRAPHICS LLC (US) 2000-05-16 US disclosed
EP-0634693-B1 Method for making direct-positive photographic images AGFA GEVAERT NV (BE) 1999-10-20 EP disclosed
US-5939233-A PHOTOGRAPHIC FILMS WITH SULFONAMIDO HYDRAZIDES HAVING PYRIDINIUM GROUPS KODAK POLYCHROME GRAPHICS LLC (US) 1999-08-17 US disclosed
EP-0634693-A1 Method for making direct-positive photographic images AGFA-GEVAERT N.V. (BE) 1995-01-18 EP disclosed
EP-0352222-B1 Fibre-reactive formazane dyes, process for their preparation and their use CIBA GEIGY AG (CH) 1994-05-25 EP disclosed
US-5114430-A Colorfast dyes that react with fibers to form red, orange or red color CIBA-GEIGY CORPORATION (US) 1992-05-19 US disclosed
US-4994562-A Colorfast; for dyeing wool, silk CIBA-GEIGY CORPORATION (US) 1991-02-19 US disclosed
EP-0352222-A2 Fibre-reactive formazane dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1990-01-24 EP disclosed