SCHEMBL7440868

SCHEMBL7440868

NS(=O)(=O)c1ccc(NC(=O)CCl)cc1

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.74
CA1 P00915 15/20 0.72
CA2 P00918 15/20 0.72
CA9 Q16790 9/20 0.70
CA12 O43570 7/20 0.70
KMT2A Q03164 2/20 0.70
MEN1 O00255 1/20 0.70
CA7 P43166 3/20 0.68
CA4 P22748 2/20 0.68
CA14 Q9ULX7 3/20 0.66
MAPT P10636 1/20 0.64
CA5A P35218 1/20 0.62
CA5B Q9Y2D0 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17510035 0.86 CA1 (0.77) CA1CA2CA9CA12KMT2A
SCHEMBL10996832 0.85 PRMT1 (1.00) PRMT1CA1CA2CA9CA12
SCHEMBL8047403 0.84 PRMT1 (0.77) PRMT1CA1CA2CA9CA12
SCHEMBL14155782 0.84 PRMT1 (0.77) PRMT1CA1CA2CA9CA12
SCHEMBL9780028 0.84 CA1 (1.00) CA1CA2CA9CA12KMT2A
SCHEMBL9081388 0.82 NPC1 (0.76) PRMT1KMT2AMEN1MAPT
SCHEMBL23388362 0.82 CA1 (0.72) CA1CA2CA9CA12KMT2A
Potassium Ion SCHEMBL11518837 0.82 PRMT1 (0.74) PRMT1CA1CA2CA9CA12
SCHEMBL5806411 0.82 CA1 (0.76) CA1CA2CA9CA12KMT2A
SCHEMBL13263684 0.82 CA1 (1.00) CA1CA2CA9CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529345-A Antibacterial cellulose modified polylactic acid and preparation method thereof 长春市快快网络科技有限公司 2025-02-28 CN claimed
WO-2022055467-A1 CERTAIN NEW 4-(2-((5-(SUBSTITUTEDAMINO)-1,3,4-THIADIAZOLE-2-YL)THIO)ACETYL)BENZENESULPHONEAMIDE DERIVATIVES AND A METHOD FOR THE SYNTHESIS OF SAID DERIVATIVES Anadolu Üniversitesi (TR) 2022-03-17 WO claimed
US-9598361-B1 Amino substituted acetamide derivative KING SAUD UNIVERSITY (SA) 2017-03-21 US claimed
EP-2987533-A1 7-substituted piperazin-1-yl fluoroquinolone compounds, their use in the treatment of cancer, pharmaceutical compositions and a method for preparation King Saud University (SA) 2016-02-24 EP claimed
CN-119529345-A Antibacterial cellulose modified polylactic acid and preparation method thereof 长春市快快网络科技有限公司 2025-02-28 CN disclosed
US-12139461-B1 Piperidine compounds as PDE5 inhibitors KING SAUD UNIVERSITY (SA) 2024-11-12 US disclosed
CN-116987032-A 4-piperazine amide benzenesulfonamide-1, 8-naphthalimide derivative, and preparation method and application thereof 桂林医学院 2023-11-03 CN disclosed
WO-2022055467-A1 CERTAIN NEW 4-(2-((5-(SUBSTITUTEDAMINO)-1,3,4-THIADIAZOLE-2-YL)THIO)ACETYL)BENZENESULPHONEAMIDE DERIVATIVES AND A METHOD FOR THE SYNTHESIS OF SAID DERIVATIVES Anadolu Üniversitesi (TR) 2022-03-17 WO disclosed
CN-107922345-B Arylsulfonamide compounds as carbonic anhydrase inhibitors and their therapeutic use 圣诺康生命科学公司 2021-03-23 CN disclosed
US-10562859-B2 Aryl sulfonamide compounds as carbonic anhydrase inhibitors and their therapeutic use SIGNALCHEM LIFESCIENCES CORPORATION (CA) 2020-02-18 US disclosed
US-10562859-B2 Aryl sulfonamide compounds as carbonic anhydrase inhibitors and their therapeutic use SIGNALCHEM LIFESCIENCES CORPORATION (CA) 2020-02-18 US disclosed
US-20180201584-A1 ARYL SULFONAMIDE COMPOUNDS AS CARBONIC ANHYDRASE INHIBITORS AND THEIR THERAPEUTIC USE SIGNALCHEM LIFESCIENCES CORPORATION (CA) 2018-07-19 US disclosed
US-9598361-B1 Amino substituted acetamide derivative KING SAUD UNIVERSITY (SA) 2017-03-21 US disclosed
US-9598361-B1 Amino substituted acetamide derivative KING SAUD UNIVERSITY (SA) 2017-03-21 US disclosed
US-9598361-B1 Amino substituted acetamide derivative KING SAUD UNIVERSITY (SA) 2017-03-21 US disclosed
WO-2017004543-A1 ARYL SULFONAMIDE COMPOUNDS AS CARBONIC ANHYDRASE INHIBITORS AND THEIR THERAPEUTIC USE SIGNALCHEM LIFESCIENCES CORPORATION (CA) 2017-01-05 WO disclosed
EP-2987533-A1 7-substituted piperazin-1-yl fluoroquinolone compounds, their use in the treatment of cancer, pharmaceutical compositions and a method for preparation King Saud University (SA) 2016-02-24 EP disclosed
US-8933267-B2 Compounds for use as anti-ulcer agent and/or anti-Helicobacter pylori agent and pharmaceutical compositions thereof KING SAUD UNIVERSITY (SA) 2015-01-13 US disclosed
US-20140329778-A1 COMPOUNDS FOR USE AS ANTI-ULCER AGENT AND/OR ANTI-HELICOBACTER PYLORI AGENT AND PHARMACEUTICAL COMPOSITIONS THEREOF KING SAUD UNIVERSITY (SA) 2014-11-06 US disclosed
US-4499100-A CARDIOUVASCULAR DISORDERS SYNTEX (U.S.A.) INC. (US) 1985-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10562859-B2 Aryl sulfonamide compounds as carbonic anhydrase inhibitors and their therapeutic use CA9, CA4, CA7 PRMT1 4040/4885CA1 8/4885CA2 5/4885
US-20180201584-A1 ARYL SULFONAMIDE COMPOUNDS AS CARBONIC ANHYDRASE INHIBITORS AND THEIR THERAPEUTIC USE CA9, CA4, CA7 PRMT1 4040/4885CA1 8/4885CA2 5/4885
US-12139461-B1 Piperidine compounds as PDE5 inhibitors PDE5A, PDE3A, PDE2A PRMT1 193/4885CA1 4783/4885CA2 3683/4885
US-20140329778-A1 COMPOUNDS FOR USE AS ANTI-ULCER AGENT AND/OR ANTI-HELICOBACTER PYLORI AGENT AND PHARMACEUTICAL COMPOSITIONS THEREOF HRH2, HRH1, HRH4 PRMT1 3518/4885CA1 3886/4885CA2 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.