Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694944 | 0.80 | TSHR (0.41) | TSHRSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL11362089 | 0.66 | AURKA (0.44) | TSHRCYP2C19KMT2AALDH1A1POLB | |
| SCHEMBL30523470 | 0.66 | AURKA (0.44) | TSHRCYP2C19KMT2AALDH1A1POLB | |
| SCHEMBL19169848 | 0.65 | TSHR (0.31) | TSHR | |
| SCHEMBL7221070 | 0.64 | MCOLN3 (0.45) | TSHRSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL17868871 | 0.64 | S100B (0.59) | TSHRSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL11519254 | 0.64 | SMN1; SMN2 (0.42) | TSHRSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL11521525 | 0.64 | ALDH1A1 (0.46) | TSHRSMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL8075768 | 0.63 | TTR (0.39) | TSHRSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL28240269 | 0.62 | S100B (0.39) | TSHRCYP2C19KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180503-A | FOR DYEING POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-25 | — | — | US | disclosed |
| US-4124581-A | FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |