Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KYNU | Q16719 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170678 | 0.84 | KYNU (0.47) | TTRGAAAPEX1KYNUCA2 | |
| SCHEMBL9178147 | 0.82 | TTR (0.58) | TTRAPEX1ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL3481099 | 0.81 | TTR (0.41) | TTRAPEX1HTTALDH1A1HSD17B10 | |
| SCHEMBL11017137 | 0.80 | CDK2 (0.38) | TTRAPEX1CA2CA12CA1 | |
| SCHEMBL9809407 | 0.76 | CA2 (0.43) | CA2CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11406615 | 0.75 | GAA (0.42) | TTRGAAAPEX1KYNUCA2 | |
| SCHEMBL2296085 | 0.75 | TTR (0.60) | TTRGAAAPEX1KYNUCA2 | |
| SCHEMBL9558895 | 0.74 | CA2 (0.46) | APEX1CA2CA12CA1CA4 | |
| SCHEMBL8951874 | 0.74 | CA2 (0.39) | GAAAPEX1CA2CA12CA1 | |
| SCHEMBL22814637 | 0.74 | GAA (0.35) | TTRGAAAPEX1KYNUCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703906-B1 | FIBER REACTIVE ANTHRAQUINONE DYES | DYSTAR L P (US) | 2000-08-30 | — | — | EP | disclosed |
| CN-1235992-A | Water-soluble fiber-reactive dyes, processes for their preparation and their use | HOECHST AG (DE) | 1999-11-24 | — | — | CN | disclosed |
| EP-0703906-A4 | FIBER REACTIVE ANTHRAQUINONE DYES | HOECHST CELANESE CORP (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0703906-A1 | FIBER REACTIVE ANTHRAQUINONE DYES | HOECHST CELANESE CORPORATION (US) | 1996-04-03 | — | — | EP | disclosed |
| CN-1108277-A | Water-soluble fibre-reactive dyes, their preparation and their use | HOECHST AG (DE) | 1995-09-13 | — | — | CN | disclosed |
| CN-1103417-A | Water soluble azo dyes which is reactable with fibre, preparation and application of same | HOECHST AG (DE) | 1995-06-07 | — | — | CN | disclosed |
| US-5409916-A | Brilliant violet shades; free of heavy metals | HOECHST CELANESE CORPORATION (US) | 1995-04-25 | — | — | US | disclosed |
| US-5393884-A | Water soluble blue dyes | HOECHST CELANESE CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| WO-1994029283-A1 | FIBER REACTIVE ANTHRAQUINONE DYES | HOECHST CELANESE CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |
| US-5349057-A | Water soluble azo dyes containing a cyanoamino-triazinyl-amino group and a fiber-reactive of the sulfone series | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | disclosed |
| US-5334709-A | Fiber-reactive dyes for cellulose materials, wool, polyamides; deep shades | HOECHST AG (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5310886-A | Fiber-reactive | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5278292-A | Aromatic sulfonyl water-soluble color materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5021558-A | Color strength, fastness | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |