Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555427 | 0.90 | ALDH1A1 (0.71) | TDP1ALDH1A1KMT2AMEN1GPR35 | |
| SCHEMBL11217415 | 0.81 | IDE (0.53) | TDP1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL17695176 | 0.80 | ALDH1A1 (0.67) | TDP1ALDH1A1KMT2AMEN1GPR35 | |
| SCHEMBL1124773 | 0.76 | ALDH1A1 (0.61) | TDP1ALDH1A1KMT2AGPR35GAA | |
| SCHEMBL2958562 | 0.76 | ALDH1A1 (0.92) | TDP1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL44392 | 0.75 | ALDH1A1 (1.00) | TDP1ALDH1A1KMT2AMEN1MAPK1 | |
| Benzene SCHEMBL28038982 | 0.75 | ALDH1A1 (1.00) | TDP1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL30196067 | 0.75 | ALDH1A1 (1.00) | TDP1ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL28674811 | 0.75 | ALDH1A1 (0.59) | TDP1ALDH1A1KMT2ANPC1GPR35 | |
| SCHEMBL21082742 | 0.75 | MEN1 (0.56) | TDP1ALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134888-A | LIQUID CRYSTALS | RCA CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4032470-A | LIQUID CRYSTAL MONOAZO DYES | RCA CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |