Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP9 | P55211 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51552 | 0.98 | MAOA (0.41) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL11516879 | 0.96 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| Hydrochloric Acid SCHEMBL8208617 | 0.96 | TSHR (0.44) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL11690364 | 0.96 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL4386410 | 0.96 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| SCHEMBL11519242 | 0.96 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| Water SCHEMBL3663798 | 0.96 | MAOA (0.40) | MAOACES1TSHRMAOBBCHE | |
| Bicarbonate SCHEMBL10507777 | 0.90 | TSHR (0.40) | MAOACES1TSHRMAOBBCHE | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL3097911 | 0.77 | KEAP1 (0.54) | KMT2ACA12CA9MEN1ALDH1A1 | |
| SCHEMBL61808 | 0.76 | MAOA (0.44) | MAOACES1TSHRMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144072-A | CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-03-13 | — | — | US | disclosed |