Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608658 | 0.87 | EPHX2 (0.62) | L3MBTL1HDAC1EPHX2NR1H4NAMPT | |
| SCHEMBL11519663 | 0.86 | HDAC1 (0.54) | L3MBTL1HDAC1EPHX2NR1H4NAMPT | |
| SCHEMBL6774590 | 0.86 | L3MBTL1 (0.51) | L3MBTL1HDAC1EPHX2NR1H4NAMPT | |
| SCHEMBL14305174 | 0.86 | L3MBTL1 (0.51) | L3MBTL1HDAC1EPHX2NR1H4NAMPT | |
| SCHEMBL5987090 | 0.84 | EPHX2 (0.58) | L3MBTL1HDAC1EPHX2NR1H4NAMPT | |
| SCHEMBL3180689 | 0.83 | L3MBTL1 (0.61) | L3MBTL1HDAC1NAMPTGAACA1 | |
| SCHEMBL11521521 | 0.82 | L3MBTL1 (0.55) | L3MBTL1HDAC1NAMPTGAACA1 | |
| SCHEMBL10227120 | 0.82 | FAAH (0.64) | L3MBTL1HDAC1CA1CA2CA12 | |
| SCHEMBL595225 | 0.82 | CA12 (0.52) | L3MBTL1HDAC1NAMPTGAACA1 | |
| SCHEMBL3806574 | 0.82 | HDAC1 (0.47) | L3MBTL1HDAC1EPHX2NR1H4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |