Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608658 | 0.87 | EPHX2 (0.62) | L3MBTL1HDAC1MEN1KMT2AMAPT | |
| SCHEMBL1668726 | 0.86 | ALDH1A1 (0.54) | L3MBTL1HDAC1NAMPTALDH1A1LMNA | |
| SCHEMBL7621920 | 0.86 | PTPN1 (0.51) | KMT2AMAPTGAANAMPTALDH1A1 | |
| SCHEMBL11519663 | 0.86 | HDAC1 (0.54) | L3MBTL1HDAC1MAPTEPHX2NR1H4 | |
| SCHEMBL14305174 | 0.86 | L3MBTL1 (0.51) | L3MBTL1HDAC1MAPTEPHX2NR1H4 | |
| SCHEMBL11519657 | 0.86 | L3MBTL1 (0.51) | L3MBTL1HDAC1MAPTEPHX2NR1H4 | |
| SCHEMBL3806574 | 0.84 | HDAC1 (0.47) | L3MBTL1HDAC1MEN1KMT2AMAPT | |
| SCHEMBL7652554 | 0.84 | NPC1 (0.58) | L3MBTL1HDAC1MEN1KMT2AMAPT | |
| SCHEMBL5987090 | 0.84 | EPHX2 (0.58) | L3MBTL1HDAC1MAPTEPHX2NR1H4 | |
| SCHEMBL23462113 | 0.83 | L3MBTL1 (0.54) | L3MBTL1HDAC1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208089-B1 | DIAZOCIN-DIONE DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | ALTANA PHARMA AG (DE) | 2004-10-13 | — | — | EP | disclosed |
| US-6673786-B1 | TREATING ALLERGIC OR INFLAMMATORY DISORDERS | ALTANA PHARMA AG (DE) | 2004-01-06 | — | — | US | disclosed |
| EP-1208089-A2 | DIAZOCIN-DIONE DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010848-A2 | DIAZOCIN-DIONE DERIVATIVES AND THEIR USE S TRYPTASE INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-02-15 | — | — | WO | disclosed |