SCHEMBL11519781

SCHEMBL11519781

CC(=O)Nc1cc(NC(=O)C(F)(F)F)cc(C(C)=O)c1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.68
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GAA P10253 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19317529 0.91 L3MBTL1 (0.54) L3MBTL1LMNAALDH1A1MAPTCYP1A2
SCHEMBL11518894 0.91 L3MBTL1 (0.79) L3MBTL1HDAC1HDAC7HDAC8HDAC6
SCHEMBL10194215 0.83 L3MBTL1 (0.47) L3MBTL1HDAC1HDAC7HDAC8HDAC6
SCHEMBL14144013 0.83 L3MBTL1 (0.47) L3MBTL1LMNAALDH1A1MAPTCYP1A2
SCHEMBL1168699 0.81 L3MBTL1 (0.45) L3MBTL1LMNAALDH1A1MAPTCYP1A2
SCHEMBL1875367 0.79 L3MBTL1 (0.73) L3MBTL1ALDH1A1MAPTGAATDP1
SCHEMBL3200467 0.78 MEN1 (0.53) L3MBTL1LMNACYP1A2CYP2C9CYP2C19
SCHEMBL7428282 0.77 MAPT (0.60) L3MBTL1HDAC1HDAC7HDAC8HDAC6
SCHEMBL23412709 0.77 LMNA (0.48) L3MBTL1HDAC1LMNAALDH1A1TP53
SCHEMBL3071609 0.74 LMNA (0.71) L3MBTL1LMNAALDH1A1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4157450-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1979-06-05 US disclosed
US-4115451-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-09-19 US disclosed
US-4071555-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-01-31 US disclosed