SCHEMBL3200467

SCHEMBL3200467

O=C(O)c1cc(NC(=O)C(F)(F)F)cc(NC(=O)C(F)(F)F)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
L3MBTL1 Q9Y468 3/20 0.51
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
LMNA P02545 1/20 0.43
GPR35 Q9HC97 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712088 0.82 L3MBTL1 (0.63) MEN1KMT2AL3MBTL1POLBCA12
SCHEMBL1820719 0.80 KDM4E (0.57) MEN1KMT2AL3MBTL1POLBCYP1A2
SCHEMBL434636 0.80 CA12 (0.56) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL19317529 0.78 L3MBTL1 (0.54) MEN1KMT2AL3MBTL1CYP1A2CYP2C9
SCHEMBL11519781 0.78 L3MBTL1 (0.68) MEN1KMT2AL3MBTL1CYP1A2CYP2C9
SCHEMBL11518894 0.78 L3MBTL1 (0.79) MEN1KMT2AL3MBTL1CYP1A2CYP2C9
SCHEMBL13901286 0.78 L3MBTL1 (0.53) MEN1KMT2AL3MBTL1POLBPKM
SCHEMBL7792756 0.78 L3MBTL1 (0.53) MEN1KMT2AL3MBTL1CYP1A2CYP2C9
SCHEMBL7080547 0.78 L3MBTL1 (0.53) MEN1KMT2AL3MBTL1POLBCYP1A2
SCHEMBL16487244 0.76 MEN1 (0.71) MEN1KMT2AL3MBTL1POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7670512-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-7670512-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-7671141-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-7671141-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-7670512-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-7671141-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-20070004873-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070004873-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070004873-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070001154-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070001154-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070001154-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed