Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520913 | 0.81 | CA2 (0.46) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL9596596 | 0.81 | PTPN1 (0.49) | CA2CA1MEN1KMT2AGAA | |
| SCHEMBL11451869 | 0.79 | HSP90AA1 (0.48) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL9501222 | 0.76 | CA2 (0.38) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL818804 | 0.75 | CA2 (0.52) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL11518256 | 0.74 | TDP1 (0.41) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL8911876 | 0.74 | CA2 (0.39) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL11655730 | 0.72 | CA2 (0.48) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL8496737 | 0.72 | PTGS1 (0.40) | ALDH1A1CA2SMN1; SMN2POLBTYR | |
| SCHEMBL8582964 | 0.72 | PTGS2 (0.39) | ALDH1A1CA2SMN1; SMN2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152319-A | ALPHA, BETA-UNSATURATED AMIDES HAVING STERICALLY HINDERED PHENOLIC GROUP | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-05-01 | — | — | US | disclosed |