Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496737 | 0.88 | PTGS1 (0.40) | CA2CA1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL8582964 | 0.85 | PTGS2 (0.39) | CA2CA1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL8501142 | 0.83 | PTGS1 (0.36) | CA2CA1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL8579119 | 0.78 | CYP1A2 (0.40) | CA2CA1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL11519790 | 0.74 | ALDH1A1 (0.50) | CA2CA1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL8583061 | 0.73 | HSPA5 (0.32) | PTGS2SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8580639 | 0.73 | CA2 (0.39) | CA2CA1PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL11518256 | 0.73 | TDP1 (0.41) | CA2CA1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8583284 | 0.72 | PTGS2 (0.31) | PTGS1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL11451869 | 0.72 | HSP90AA1 (0.48) | CA2CA1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691367-A | ANTIINFLAMMATORY AGENTS OR ANTIARTHRITIC AGENTS | ELI LILLY AND COMPANY (US) | 1997-11-25 | — | — | US | disclosed |