Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11519865 | 1.00 | NFE2L2 (0.51) | NFE2L2TRPA1TNFRSF1AMAPTNPSR1 | |
| SCHEMBL28658747 | 0.86 | MAPT (0.60) | NFE2L2TRPA1MAPTNPSR1CYP1A1 | |
| SCHEMBL6233121 | 0.86 | MAPT (0.61) | NFE2L2TRPA1MAPTNPSR1CYP1A1 | |
| SCHEMBL6233123 | 0.86 | MAPT (0.61) | NFE2L2TRPA1MAPTNPSR1CYP1A1 | |
| SCHEMBL28485401 | 0.76 | MAPT (0.48) | NFE2L2TRPA1TNFRSF1AMAPTNPSR1 | |
| SCHEMBL9515990 | 0.76 | CA1 (0.69) | CYP1A2KMT2ACYP3A4CA12CA1 | |
| SCHEMBL16191542 | 0.75 | MAPT (0.57) | NFE2L2TRPA1MAPTNPSR1CYP1A1 | |
| SCHEMBL16191546 | 0.75 | MAPT (0.57) | NFE2L2TRPA1MAPTNPSR1CYP1A1 | |
| SCHEMBL30358578 | 0.75 | MAPT (0.57) | NFE2L2TRPA1MAPTNPSR1CYP1A1 | |
| SCHEMBL9729072 | 0.75 | TNFRSF1A (0.59) | NFE2L2TRPA1TNFRSF1AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172949-A | 2,4-Disubstituted-5-oxo-5H-dibenzo[a,d]cycloheptenes | SYNTEX (U.S.A.) INC. (US) | 1979-10-30 | — | — | US | disclosed |