Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233123 | 1.00 | MAPT (0.61) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL28658747 | 0.86 | MAPT (0.60) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL11519871 | 0.86 | NFE2L2 (0.51) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL11519865 | 0.86 | NFE2L2 (0.51) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL27900296 | 0.81 | TUBB1 (0.63) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL30358577 | 0.80 | SLC5A1 (0.61) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL6229522 | 0.80 | SLC5A1 (0.61) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL6229519 | 0.80 | SLC5A1 (0.61) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL2222203 | 0.80 | MAOA (0.66) | MAPTKMT2ANPSR1MEN1KCNA3 | |
| SCHEMBL30358571 | 0.80 | MAOA (0.66) | MAPTKMT2ANPSR1MEN1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311257-B1 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INC (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1311257-A2 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | Insmed Incorporated (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6552085-B2 | For lowering blood glucose in a mammal | INSMED INCORPORATED | 2003-04-22 | — | — | US | disclosed |
| US-6410596-B1 | FOR LOWERING BLOOD GLUCOSE IN A MAMMAL | INSMED INCORPORATED | 2002-06-25 | — | — | US | disclosed |
| US-20020058707-A1 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED | 2002-05-16 | — | — | US | disclosed |
| US-20020058701-A1 | Compositions containing hypoglycemically active stilbenoids | SHAMAN PHARMACEUTICALS | 2002-05-16 | — | — | US | disclosed |
| WO-2002013811-A2 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | disclosed |
| WO-2002014252-A2 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058707-A1 | COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS | SLC5A2, SLC5A1, SLC2A1 | MAPT 1882/4885KMT2A 1395/4885NPSR1 3256/4885 |
| US-20020058701-A1 | Compositions containing hypoglycemically active stilbenoids | SLC5A2, SLC5A1, SLC2A1 | MAPT 1882/4885KMT2A 1395/4885NPSR1 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.