Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162970 | 0.83 | MAPT (0.50) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL11527141 | 0.82 | GAA (0.48) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL10946042 | 0.82 | GAA (0.48) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL4401042 | 0.82 | GAA (0.48) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL1426410 | 0.80 | TUBB4A (0.47) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL7953864 | 0.80 | ALDH1A1 (0.47) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL25345941 | 0.78 | GAA (0.45) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL30038976 | 0.78 | GAA (0.50) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL31506852 | 0.78 | MAPT (0.48) | CYP3A4ALDH1A1GAANPC1MAPT | |
| SCHEMBL1438002 | 0.78 | THRB (0.60) | CYP3A4ALDH1A1GAANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165319-A | Isoindoline pigments | CIBA-GEIGY CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |