Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521075 | 0.82 | HSP90AA1 (0.46) | HSP90AA1APPLMNATSHRPGR | |
| SCHEMBL11521948 | 0.80 | APP (0.60) | HSP90AA1APPXDHLMNAMMP13 | |
| SCHEMBL11566254 | 0.76 | KMO (0.48) | HSP90AA1APPLMNATSHRPGR | |
| SCHEMBL11520329 | 0.74 | APP (0.56) | APPLMNAMEN1KMT2AACKR3 | |
| SCHEMBL31405188 | 0.73 | HSP90AA1 (0.77) | HSP90AA1LMNATSHRKMT2APDE7A | |
| SCHEMBL11356136 | 0.73 | HSP90AA1 (0.77) | HSP90AA1LMNATSHRKMT2APDE7A | |
| SCHEMBL11520999 | 0.72 | APP (0.57) | APPLMNAMEN1KMT2APKM | |
| SCHEMBL11521568 | 0.69 | APP (0.53) | APPXDHLMNAMEN1KMT2A | |
| SCHEMBL2887765 | 0.69 | HSP90AA1 (0.69) | HSP90AA1LMNATSHRMEN1KMT2A | |
| SCHEMBL2179103 | 0.69 | APP (0.66) | APPLMNATSHRPGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | claimed |
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |