Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522659 | 0.91 | ADRB2 (0.63) | ADRB2ADRB1ADRB3 | |
| SCHEMBL11524998 | 0.87 | ADRB2 (0.70) | ADRB2ADRB1ADRB3LMNAHTR1A | |
| SCHEMBL11522642 | 0.86 | ADRB3 (0.70) | ADRB2ADRB1ADRB3LMNAHTR1A | |
| SCHEMBL11522665 | 0.86 | ADRB3 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL11526078 | 0.84 | ADRB2 (0.44) | ADRB2ADRB1ADRB3LMNAHTR1A | |
| SCHEMBL11524202 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1ADRB3LMNAHTR1A | |
| SCHEMBL9684040 | 0.82 | ADRB3 (0.87) | ADRB2ADRB1ADRB3HTR1ASLC6A2 | |
| SCHEMBL9685312 | 0.82 | ADRB3 (0.87) | ADRB2ADRB1ADRB3HTR1ASLC6A2 | |
| SCHEMBL9684048 | 0.82 | ADRB3 (0.87) | ADRB2ADRB1ADRB3HTR1ASLC6A2 | |
| SCHEMBL11521385 | 0.81 | ADRB2 (0.66) | ADRB2ADRB1ADRB3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | claimed |
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | disclosed |