Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522642 | 0.86 | ADRB3 (0.70) | ADRB2ADRB3ADRB1CYP2D6HTR2A | |
| SCHEMBL11522665 | 0.84 | ADRB3 (0.69) | ADRB2ADRB3ADRB1CYP2D6CYP1A2 | |
| SCHEMBL10434592 | 0.82 | ADRB2 (0.67) | ADRB2ADRB3ADRB1CYP2D6HTR2A | |
| SCHEMBL11520092 | 0.82 | ADRB2 (0.66) | ADRB2ADRB3ADRB1SLC6A4ADRA1A | |
| SCHEMBL11522659 | 0.80 | ADRB2 (0.63) | ADRB2ADRB3ADRB1 | |
| SCHEMBL9684040 | 0.80 | ADRB3 (0.87) | ADRB2ADRB3ADRB1CYP2D6SLC6A4 | |
| SCHEMBL9684048 | 0.80 | ADRB3 (0.87) | ADRB2ADRB3ADRB1CYP2D6SLC6A4 | |
| SCHEMBL9685312 | 0.80 | ADRB3 (0.87) | ADRB2ADRB3ADRB1CYP2D6SLC6A4 | |
| SCHEMBL11521385 | 0.80 | ADRB2 (0.66) | ADRB2ADRB3ADRB1CYP2D6HTR2A | |
| SCHEMBL11522246 | 0.79 | CASR (0.63) | ADRB2ADRB3ADRB1CYP2D6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | claimed |
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | disclosed |