Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19585472 | 0.84 | HTT (0.43) | MEN1KMT2AMAPTLMNACA1 | |
| SCHEMBL19585927 | 0.82 | HTT (0.42) | MEN1KMT2AMAPTLMNACA12 | |
| SCHEMBL11518725 | 0.81 | LTA4H (0.49) | CA12CA1CA2CA9 | |
| SCHEMBL19585867 | 0.79 | HPGD (0.46) | MEN1KMT2AMAPTPOLBHTT | |
| SCHEMBL4440928 | 0.76 | MAPT (0.48) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL11520215 | 0.76 | LMNA (0.39) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL7203394 | 0.74 | ALDH1A1 (0.56) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL5705068 | 0.73 | MAPT (0.46) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL11517933 | 0.73 | MEN1 (0.51) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL11528868 | 0.72 | HDAC8 (0.52) | MEN1KMT2AMAPTHTTHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |