SCHEMBL11520486

SCHEMBL11520486

O=C([C](F)F)C(F)(F)C(=O)C(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22208158 0.72 ALDH1A1 (0.32)
SCHEMBL16993775 0.70
SCHEMBL3953386 0.70
SCHEMBL2884062 0.69 PKM (0.39) PKM
SCHEMBL28256603 0.68
SCHEMBL8447002 0.68
SCHEMBL891845 0.67
SCHEMBL4104149 0.64
SCHEMBL9935877 0.63
SCHEMBL395056 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180386-A ANTIKNOCK FUEL ADDITIVES E. I. DU PONT DE NEMOURS & COMPANY (US) 1979-12-25 US claimed
CN-115043772-A Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane 浙江新和成股份有限公司 2022-09-13 CN disclosed
CN-114591217-A Process for the preparation of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediates thereof 浙江新和成股份有限公司 2022-06-07 CN disclosed