Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537769 | 0.76 | TSHR (0.47) | TSHRRGS12GAABACE1 | |
| SCHEMBL631670 | 0.75 | TSHR (0.41) | TSHRRGS12BACE1KDM4E | |
| SCHEMBL1332682 | 0.70 | TSHR (0.42) | TSHRRGS12GAATDP1 | |
| SCHEMBL6250456 | 0.68 | TSHR (0.40) | TSHRRGS12TDP1 | |
| SCHEMBL11420895 | 0.68 | TSHR (0.40) | TSHRRGS12TDP1 | |
| SCHEMBL18009179 | 0.67 | NFE2L2 (0.43) | TSHRRGS12GAAKDM4E | |
| SCHEMBL8402767 | 0.66 | ESR1 (0.46) | TSHRGAATDP1KDM4E | |
| SCHEMBL854268 | 0.66 | RGS12 (0.38) | TSHRRGS12TDP1 | |
| SCHEMBL19755145 | 0.66 | CHRNA7 (0.49) | GAAPTPN2PTPN1PTPRFCHRNA7 | |
| SCHEMBL5320949 | 0.66 | HTT (0.42) | GAAPTPN2PTPN1PTPRFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141928-A | POLYOXYALKYLATED HYDANTOIN, BLOCK POLYMERS | MONSANTO COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4122072-A | FIBERS, MODIFIED BY HYDANTOIN DERIVATIVES | MONSANTO COMPANY (US) | 1978-10-24 | — | — | US | disclosed |