Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537769 | 0.81 | TSHR (0.47) | TSHRRGS12HSD17B10BACE1ALDH1A1 | |
| SCHEMBL1332682 | 0.79 | TSHR (0.42) | TSHRRGS12HSD17B10ALDH1A1HTT | |
| SCHEMBL27655606 | 0.78 | TSHR (0.40) | TSHRRGS12BACE1 | |
| SCHEMBL6250456 | 0.76 | TSHR (0.40) | TSHRRGS12ALDH1A1HTTMEN1 | |
| SCHEMBL11520501 | 0.75 | TSHR (0.38) | TSHRRGS12BACE1KDM4E | |
| SCHEMBL2678789 | 0.73 | TSHR (0.38) | TSHRRGS12ALDH1A1HTTMEN1 | |
| SCHEMBL11241509 | 0.73 | TSHR (0.36) | TSHRRGS12POLBHSD17B10BACE1 | |
| SCHEMBL6232872 | 0.73 | — | — | |
| SCHEMBL854710 | 0.70 | RGS12 (0.33) | TSHRRGS12ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6813692 | 0.70 | LMNA (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | claimed |
| EP-0628571-A1 | NOVEL PEPTIDE, AND ANTITHROMBOTIC AGENT, ANTICOAGULANT FOR EXTRACORPOREAL CIRCULATION, CELL FUSION INHIBITOR, CANCER METASTASIS INHIBITOR, PROTECTIVE FOR PLATELET PREPARATION FOR TRANSFUSION AND PACK OF PLATELET PREPARATION FOR TRANSFUSION | NIPPON STEEL CORPORATION (JP) | 1994-12-14 | — | — | EP | claimed |
| EP-0422765-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1991-04-17 | — | — | EP | claimed |
| CN-110278711-B | Tricyclosulfones as rory modulators | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-109153644-B | Small molecules against CEREBLON to enhance effector T cell function | H·李·莫菲特癌症中心研究有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-101379138-B | Conductive polymer solution, conductive coating film, capacitor and method for producing same | 信越聚合物株式会社 | 2019-03-22 | — | — | CN | disclosed |
| CN-109153644-A | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H·李·莫菲特癌症中心研究有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108299987-A | The preparation method of the amine additives of conductive composite body and its preparation method of solution and conductive film | 信越聚合物株式会社 | 2018-07-20 | — | — | CN | disclosed |
| CN-108028133-A | The manufacture method of conductive-polymer solution, capacitor and capacitor | 信越聚合物株式会社 | 2018-05-11 | — | — | CN | disclosed |
| CN-107603357-A | Electric conductivity release layer formation coating and its manufacture method and electric conductivity mold release film and its manufacture method | 信越聚合物株式会社 | 2018-01-19 | — | — | CN | disclosed |
| CN-107001801-A | Addition hardening antistatic organopolysiloxane composition and antistatic silicone epithelium | 信越聚合物株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-1125054-C | Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMACEUTICS GMBH (DE) | 2003-10-22 | — | — | CN | disclosed |
| CN-1267210-A | Hair styling composition | PROCTER & GAMBLE (US) | 2000-09-20 | — | — | CN | disclosed |
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| CN-1218047-A | Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | HOECHST MARION ROUSSEL DE GMBH (DE) | 1999-06-02 | — | — | CN | disclosed |
| CN-1037975-C | Curable suspensions of epoxy resins | CIBA GEIGY AG (CH) | 1998-04-08 | — | — | CN | disclosed |
| US-5498601-A | RGD SEQUENCE | NIPPON STEEL CORPORATION (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0628571-A1 | NOVEL PEPTIDE, AND ANTITHROMBOTIC AGENT, ANTICOAGULANT FOR EXTRACORPOREAL CIRCULATION, CELL FUSION INHIBITOR, CANCER METASTASIS INHIBITOR, PROTECTIVE FOR PLATELET PREPARATION FOR TRANSFUSION AND PACK OF PLATELET PREPARATION FOR TRANSFUSION | NIPPON STEEL CORPORATION (JP) | 1994-12-14 | — | — | EP | disclosed |
| CN-1083082-A | Curable suspensions of epoxy resins | CIBA GEIGY AG (CH) | 1994-03-02 | — | — | CN | disclosed |
| EP-0422765-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1991-04-17 | — | — | EP | disclosed |