SCHEMBL5320949

SCHEMBL5320949

O=C1CC(OC(=O)c2ccc(C(=O)OC3CC(=O)NC3=O)cc2)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
POLB P06746 1/20 0.39
TP53 P04637 1/20 0.37
MAPK1 P28482 1/20 0.37
GAA P10253 1/20 0.37
GPR39 O43194 1/20 0.37
DDB1 Q16531 4/20 0.37
CRBN Q96SW2 4/20 0.37
PTPN2 P17706 2/20 0.37
PTPN1 P18031 2/20 0.37
PTPRF P10586 1/20 0.37
MAP3K14 Q99558 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068302 0.92 GAA (0.48) GAADDB1CRBNALDH1A1
Ammonia Solution, Strong SCHEMBL9774304 0.90 GAA (0.47) GAADDB1CRBNALDH1A1
SCHEMBL6510960 0.89 ALDH1A1 (0.45) HTTPOLBTP53MAPK1GAA
SCHEMBL8997420 0.89 HTT (0.35) HTTPOLBTP53MAPK1GAA
SCHEMBL9838641 0.87 PTPN2 (0.53) POLBMAPK1CRBNPTPN2PTPN1
SCHEMBL660307 0.85 GAA (0.43) GAADDB1CRBNKDM4EALDH1A1
SCHEMBL3675740 0.81 ALDH1A1 (0.48) GAAKDM4EALDH1A1
SCHEMBL3949247 0.77 MAP3K14 (0.40) GAADDB1CRBNMAP3K14KDM4E
SCHEMBL7264550 0.77 MAP3K14 (0.40) GAADDB1CRBNMAP3K14CYP19A1
SCHEMBL5956001 0.76 MGLL (0.42) HTTMAPK1GAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007088992-A1 LIGHT TRANSMITTING ELECTROMAGNETIC WAVE SHIELDING FILM, OPTICAL FILTER AND PLASMA DISPLAY PANEL FUJIFILM CORPORATION (JP) 2007-08-09 WO disclosed