SCHEMBL11520643

SCHEMBL11520643

NC(=O)OC(CO)CCO

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
MAPK1 P28482 1/20 0.35
LMNA P02545 2/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
PRKCA P17252 2/20 0.31
PRKCE Q02156 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCD Q05655 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28331579 1.00 MAPT (0.35) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL28522874 0.86 MAPT (0.33) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL2480097 0.85
SCHEMBL28658685 0.84 LMNA (0.33) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL28658682 0.84 LMNA (0.33) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL28772648 0.83 MAPT (0.35) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL31232292 0.82 ANPEP (0.33) MAPTLMNACHRM2CHRM4CHRM5
SCHEMBL11757686 0.82 PRKCA (0.38) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL1437005 0.82 MAPT (0.41) MAPTMAPK1LMNACHRM2CHRM4
SCHEMBL10581048 0.80 CTSK (0.38) MAPTMAPK1LMNACHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181468-B Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2024-03-05 CN claimed
CN-115232528-A Super-hydrophilic antibacterial coating sol and preparation method and application thereof 泉州师范学院 2022-10-25 CN claimed
CN-115181468-A Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2022-10-14 CN claimed
US-4168336-A MICROCELLULAR POLYURETHANE CORE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-09-18 US claimed
CN-112638898-B Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors 泽农医药公司 2024-04-09 CN disclosed
CN-115181468-B Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2024-03-05 CN disclosed
CN-112351778-B Fused tricyclic heterocycles and therapeutic uses thereof 江苏恒瑞医药股份有限公司 2023-04-04 CN disclosed
CN-115232528-A Super-hydrophilic antibacterial coating sol and preparation method and application thereof 泉州师范学院 2022-10-25 CN disclosed
CN-115181468-A Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2022-10-14 CN disclosed
CN-112638898-A Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors 泽农医药公司 2021-04-09 CN disclosed
CN-109526219-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2021-03-12 CN disclosed
CN-112351778-A Fused tricyclic heterocycles and therapeutic uses thereof 江苏恒瑞医药股份有限公司 2021-02-09 CN disclosed
CN-105792852-B Glucose-responsive insulin conjugates 默沙东公司 2019-12-10 CN disclosed
US-4168336-A MICROCELLULAR POLYURETHANE CORE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-09-18 US disclosed
US-4070345-A N,N-DIHYDROXYALKYL HYDRAZINES, ALKOXYMETHYL ISOCYANATES BAYER AKTIENGESELLSCHAFT (DT) 1978-01-24 US disclosed