SCHEMBL11520901

SCHEMBL11520901

CC(Cl)(C(=O)O)c1c(Br)c(Br)c(Br)c(C(C)(Cl)C(=O)O)c1Br

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11522674 0.75 ALDH1A1 (0.38) ALDH1A1TSHRTP53
SCHEMBL11028003 0.67 ALDH1A1 (0.31) ALDH1A1TSHRTP53
SCHEMBL5944823 0.64
Dalapon SCHEMBL4895986 0.63 TSHR (0.57) ALDH1A1TSHRTP53
Dalapon SCHEMBL45164 0.63
SCHEMBL301323 0.63
SCHEMBL1678472 0.63 TSHR (0.57) ALDH1A1TSHRTP53
SCHEMBL29613223 0.62 CYP1A2 (0.60) ALDH1A1TSHR
SCHEMBL305060 0.62 CYP1A2 (0.60) ALDH1A1TSHR
Dalapon SCHEMBL4446142 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141912-A Process for the preparation of polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-02-27 US disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed