SCHEMBL11522149

SCHEMBL11522149

Cc1ccc(-c2ccc(-c3ccccc3-c3ccccc3)s2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.45
NQO2 P16083 3/20 0.43
HSD17B1 P14061 4/20 0.43
HSD17B2 P37059 4/20 0.43
RAB9A P51151 3/20 0.41
POLB P06746 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
APP P05067 2/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 1/20 0.39
HPRT1 P00492 1/20 0.39
ALOX5 P09917 1/20 0.39
NPC1 O15118 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
PTGS2 P35354 1/20 0.39
CYP2E1 P05181 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015219 0.88 RXFP1 (0.53) RXFP1NQO2HSD17B1HSD17B2RAB9A
SCHEMBL14037011 0.86 RXFP1 (0.51) RXFP1NQO2HSD17B1HSD17B2RAB9A
SCHEMBL11522143 0.86 MEN1 (0.52) RXFP1NQO2HSD17B1HSD17B2RAB9A
SCHEMBL14190038 0.84 HSD17B1 (0.56) NQO2HSD17B1HSD17B2RAB9APOLB
SCHEMBL31197633 0.82 APP (0.45) NQO2HSD17B1HSD17B2APPCYP3A4
SCHEMBL20184172 0.82 APP (0.45) NQO2HSD17B1HSD17B2APPCYP3A4
SCHEMBL12854019 0.82 HSD17B1 (0.54) NQO2HSD17B1HSD17B2RAB9APOLB
SCHEMBL14190043 0.82 HSD17B1 (0.54) NQO2HSD17B1HSD17B2RAB9APOLB
SCHEMBL29688196 0.82 LMNA (0.53) RAB9APOLBMEN1KMT2AHPRT1
SCHEMBL3294988 0.82 LMNA (0.53) RAB9APOLBMEN1KMT2AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4174405-A MITICIDES UNIROYAL, INC. (US) 1979-11-13 US disclosed