SCHEMBL6015219

SCHEMBL6015219

Cc1ccc(-c2ccc(-c3ccccc3)s2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.53
HSD17B1 P14061 6/20 0.52
HSD17B2 P37059 6/20 0.52
NQO2 P16083 3/20 0.52
POLB P06746 2/20 0.48
RAB9A P51151 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP3A4 P08684 2/20 0.47
CYP2C19 P33261 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP2E1 P05181 1/20 0.47
CYP2A6 P11509 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2B6 P20813 1/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11522143 0.98 MEN1 (0.52) RXFP1HSD17B1HSD17B2NQO2POLB
SCHEMBL14037011 0.98 RXFP1 (0.51) RXFP1HSD17B1HSD17B2NQO2POLB
SCHEMBL9968693 0.90 APP (0.55) HSD17B1HSD17B2CYP3A4CYP2C19TDP1
SCHEMBL14179953 0.88 HSD17B1 (0.54) RXFP1HSD17B1HSD17B2NQO2CYP3A4
SCHEMBL11522149 0.88 RXFP1 (0.45) RXFP1HSD17B1HSD17B2NQO2POLB
SCHEMBL12575567 0.87 APP (0.52) HSD17B1HSD17B2CYP3A4CYP2C19TDP1
SCHEMBL7587610 0.87 HSD17B1 (0.62) HSD17B1HSD17B2NQO2POLBRAB9A
SCHEMBL14190035 0.87 HSD17B1 (0.62) HSD17B1HSD17B2NQO2POLBRAB9A
SCHEMBL13125840 0.87 APP (0.54) RXFP1HSD17B1HSD17B2NQO2POLB
SCHEMBL10109359 0.85 APP (0.56) RXFP1HSD17B1HSD17B2NQO2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10873035-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. 2020-12-22 US disclosed
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. (KR) 2020-11-03 US disclosed
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2020-10-13 US disclosed
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-08-04 US disclosed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2019-09-24 US disclosed
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20110049487-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049487-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20100244008-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-09-30 US disclosed
US-20100244008-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-09-30 US disclosed
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-07-29 US disclosed
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-07-29 US disclosed
EP-1342769-B1 Organic EL Device TDK CORP (JP) 2010-01-27 EP disclosed
EP-1992672-A1 Organic electroluminescent device TDK Corporation (JP) 2008-11-19 EP disclosed
WO-2008133459-A1 NEW DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110049487-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LUMINESCENCE DEVICE USING THE SAME TYR, ICMT, INMT RXFP1 4524/4885HSD17B1 4485/4885HSD17B2 4199/4885
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 RXFP1 3608/4885HSD17B1 2267/4885HSD17B2 1858/4885
US-10800969-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 RXFP1 4565/4885HSD17B1 3110/4885HSD17B2 2187/4885
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME DDT, AOC1, DDC RXFP1 4824/4885HSD17B1 3146/4885HSD17B2 2891/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 RXFP1 3608/4885HSD17B1 2267/4885HSD17B2 1858/4885
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, PER2 RXFP1 4558/4885HSD17B1 2656/4885HSD17B2 1933/4885
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT RXFP1 4293/4885HSD17B1 3786/4885HSD17B2 3557/4885
US-10822330-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 RXFP1 4176/4885HSD17B1 2092/4885HSD17B2 1331/4885
US-20180148641-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 RXFP1 4597/4885HSD17B1 3134/4885HSD17B2 2152/4885
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same NR2E3, CRY1, CRY2 RXFP1 3495/4885HSD17B1 558/4885HSD17B2 251/4885
US-10873035-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 RXFP1 4176/4885HSD17B1 2092/4885HSD17B2 1331/4885
US-20100244008-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CRY1, PPOX, CRY2 RXFP1 4806/4885HSD17B1 1779/4885HSD17B2 1417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.