Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527728 | 0.78 | MAPT (0.40) | TSHRMAPK1HIF1ATDP1LMNA | |
| SCHEMBL11524355 | 0.75 | DPP4 (0.50) | HIF1ALMNACYP2D6 | |
| SCHEMBL20752053 | 0.72 | ADRB2 (0.56) | ADRB2IDO1TDO2TSHRMAPK1 | |
| SCHEMBL24017052 | 0.71 | ADRB2 (0.62) | ADRB2IDO1TDO2TSHRMAPK1 | |
| SCHEMBL1155851 | 0.71 | ADRB2 (0.62) | ADRB2IDO1TDO2TSHRMAPK1 | |
| SCHEMBL3678300 | 0.71 | ADRB2 (0.62) | ADRB2IDO1TDO2TSHRMAPK1 | |
| SCHEMBL1732927 | 0.71 | ADRB2 (0.62) | ADRB2IDO1TDO2TSHRMAPK1 | |
| SCHEMBL3253726 | 0.71 | ADRB2 (0.62) | ADRB2IDO1TDO2TSHRMAPK1 | |
| SCHEMBL11527756 | 0.70 | TP53 (0.57) | IDO1TDO2TSHRLMNATP53 | |
| Hydrochloric Acid SCHEMBL30098243 | 0.69 | ADRB2 (0.59) | ADRB2IDO1TDO2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147780-A | α-Amino-phosphonous acids for inhibiting bacteria and yeast | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |