Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527380 | 0.78 | CHRNA7 (0.39) | MEN1KMT2AALDH1A1TDP1PLAU | |
| SCHEMBL11522208 | 0.78 | ADRB2 (0.50) | MEN1KMT2ACYP3A4HIF1ATHRB | |
| SCHEMBL11525400 | 0.73 | ALDH1A1 (0.46) | MAPTKMT2AALDH1A1CYP3A4ALOX15 | |
| SCHEMBL22184055 | 0.70 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL12461779 | 0.69 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL9663050 | 0.69 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL2590179 | 0.69 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11526208 | 0.69 | SMN1; SMN2 (0.53) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL1357098 | 0.67 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3403037 | 0.67 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147780-A | α-Amino-phosphonous acids for inhibiting bacteria and yeast | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |