SCHEMBL11524355

SCHEMBL11524355

NC(c1ccccc1)P(O)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
ADRA2A P08913 1/20 0.44
ADRA2C P18825 1/20 0.44
LMNA P02545 1/20 0.44
HIF1A Q16665 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HTR2A P28223 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527728 0.77 MAPT (0.40) F2LMNAHIF1AKDM4EALDH1A1
SCHEMBL11522208 0.75 ADRB2 (0.50) LMNAHIF1ACYP2D6
SCHEMBL11527380 0.75 CHRNA7 (0.39) LMNAALDH1A1
SCHEMBL11526633 0.73 UGT2B7 (0.52) HIF1AALDH1A1CYP2D6
SCHEMBL6441510 0.72 SRC (0.42) DPP4F2LMNACYP2D6SRC
SCHEMBL6895608 0.70 LMNA (0.44) ADRA2AADRA2CLMNAHIF1AKDM4E
SCHEMBL11525400 0.70 ALDH1A1 (0.46) ADRA2AADRA2CALDH1A1
SCHEMBL13208856 0.69
SCHEMBL206647 0.69
SCHEMBL14957448 0.68 ADRA2C (0.44) ADRA2AADRA2CLMNAHIF1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147780-A α-Amino-phosphonous acids for inhibiting bacteria and yeast CIBA-GEIGY CORPORATION (US) 1979-04-03 US disclosed