Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17222057 | 0.90 | KDM4E (0.36) | SIRT1USP2RXFP1KDM4EALDH1A1 | |
| SCHEMBL2308095 | 0.81 | LMNA (0.36) | SIRT1ALDH1A1LMNAKMT2ASIRT2 | |
| SCHEMBL11013324 | 0.80 | IRAK4 (0.32) | SIRT1USP2RXFP1KDM4EALDH1A1 | |
| SCHEMBL11013358 | 0.80 | KDM4E (0.33) | USP2RXFP1KDM4EALDH1A1LMNA | |
| Oxalic Acid SCHEMBL3858250 | 0.79 | IRAK4 (0.40) | USP2RXFP1KDM4EALDH1A1LMNA | |
| SCHEMBL10841326 | 0.77 | SIRT1 (0.39) | SIRT1USP2RXFP1KDM4EALDH1A1 | |
| SCHEMBL14884981 | 0.77 | ACHE (0.38) | USP2RXFP1KDM4EALDH1A1LMNA | |
| SCHEMBL5111399 | 0.77 | ACHE (0.38) | USP2RXFP1KDM4EALDH1A1LMNA | |
| SCHEMBL10287319 | 0.77 | ACHE (0.38) | USP2RXFP1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11519661 | 0.77 | ADORA1 (0.37) | KDM4EALDH1A1KMT2AMEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |