Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 18/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521645 | 0.84 | CASR (0.65) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| Pargolol SCHEMBL1254705 | 0.82 | MAPT (0.67) | ADRB2CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL11525714 | 0.82 | CASR (0.62) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11511416 | 0.82 | CASR (0.59) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11143271 | 0.81 | CYP2D6 (0.65) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11522766 | 0.80 | CASR (0.60) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11524202 | 0.79 | ADRB2 (0.63) | ADRB2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11522955 | 0.79 | ADRB2 (0.62) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11225249 | 0.79 | CASR (0.73) | CASRADRB2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11226824 | 0.78 | CASR (0.76) | CASRADRB2CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | claimed |