Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525714 | 0.87 | CASR (0.62) | ADRB2ADRB3ADRB1SLC6A2SLC6A4 | |
| SCHEMBL11522766 | 0.85 | CASR (0.60) | ADRB2ADRB3ADRB1SLC6A2SLC6A4 | |
| SCHEMBL11521898 | 0.83 | ADRB2 (0.51) | ADRB2ADRB3ADRB1HTR1ALMNA | |
| SCHEMBL11845793 | 0.83 | ALDH1A1 (0.74) | ADRB2ADRB3ADRB1HTR1ALMNA | |
| SCHEMBL7317233 | 0.82 | CASR (0.59) | ADRB2ADRB3ADRB1HTR1ALMNA | |
| SCHEMBL11521645 | 0.82 | CASR (0.65) | ADRB2ADRB3ADRB1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11226416 | 0.82 | ALDH1A1 (0.73) | ADRB2ADRB3ADRB1HTR1ALMNA | |
| SCHEMBL7318229 | 0.80 | CASR (0.56) | ADRB2ADRB3ADRB1HTR1ALMNA | |
| SCHEMBL11524998 | 0.80 | ADRB2 (0.70) | ADRB2ADRB3ADRB1HTR1ALMNA | |
| SCHEMBL11143271 | 0.80 | CYP2D6 (0.65) | ADRB2ADRB3ADRB1HTR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | claimed |
| US-4161542-A | 3-(2-/P-HYDROXYPHENYL/-1-METHYLETHYLAMINO)-1-PHENOXY-2-PROPANOL/; | AKTIEBOLAGET HASSLE (SE) | 1979-07-17 | — | — | US | disclosed |