Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521825 | 0.91 | LMNA (0.44) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11523181 | 0.89 | LMNA (0.36) | LMNATSHRMAPK1SMN1; SMN2CNR1 | |
| SCHEMBL11545376 | 0.89 | LMNA (0.46) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| Ammonia Solution, Strong SCHEMBL11547117 | 0.88 | LMNA (0.45) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11521316 | 0.85 | TSHR (0.49) | LMNATSHRMAPK1SMN1; SMN2CNR1 | |
| SCHEMBL4311751 | 0.84 | LMNA (0.47) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11521895 | 0.83 | LMNA (0.51) | LMNATSHRMAPK1SMN1; SMN2CNR1 | |
| Hydrochloric Acid SCHEMBL1020768 | 0.83 | LMNA (0.46) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11567195 | 0.82 | KMT2A (0.34) | LMNASMN1; SMN2CNR1CNR2KMT2A | |
| SCHEMBL11406813 | 0.82 | LMNA (0.47) | LMNATSHRMAPK1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132731-A | X-RAY CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | claimed |
| US-4132731-A | X-RAY CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |