Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL11547117 | 0.99 | LMNA (0.45) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11522281 | 0.89 | LMNA (0.45) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11547743 | 0.88 | LMNA (0.44) | LMNAHPGDHTTALDH1A1ABCC9 | |
| SCHEMBL11545562 | 0.86 | LMNA (0.41) | LMNATSHRMAPK1HPGDHTT | |
| SCHEMBL4311751 | 0.85 | LMNA (0.47) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11521825 | 0.84 | LMNA (0.44) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL1020768 | 0.84 | LMNA (0.46) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11406813 | 0.83 | LMNA (0.47) | LMNATSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL11545664 | 0.83 | LMNA (0.52) | LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11522677 | 0.81 | LMNA (0.52) | LMNATSHRMAPK1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138589-A | CHEMICAL INTERMEDIATES FOR COMPOUNDS USED AS X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4069250-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1978-01-17 | — | — | US | disclosed |