Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524084 | 0.94 | SMN1; SMN2 (0.54) | CSNK2A2CSNK2A1ALDH1A1TSHRLMNA | |
| SCHEMBL7554895 | 0.82 | SMN1; SMN2 (0.51) | CSNK2A2CSNK2A1ALDH1A1TSHRLMNA | |
| SCHEMBL1592889 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL1592377 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL8601513 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL8654517 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL1592407 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL1592334 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL1592379 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 | |
| SCHEMBL1593183 | 0.81 | RAB9A (0.53) | ALDH1A1TSHRLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160866-A | CROSSLINKERS FOR NATURAL AND SYNTHETIC RUBBERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |