Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395608 | 0.94 | LMNA (0.46) | LMNASMN1; SMN2HTTBRD4KDM4E | |
| Ioxitalamic Acid SCHEMBL455411 | 0.92 | LMNA (0.57) | LMNASMN1; SMN2BRD4KDM4ETSHR | |
| Ioxitalamic Acid SCHEMBL29815239 | 0.92 | LMNA (0.57) | LMNASMN1; SMN2BRD4KDM4ETSHR | |
| SCHEMBL12957879 | 0.83 | LMNA (0.52) | LMNASMN1; SMN2HTTBRD4MAP2K1 | |
| SCHEMBL11520893 | 0.83 | LMNA (0.50) | LMNASMN1; SMN2HTTKDM4ETSHR | |
| SCHEMBL11775063 | 0.83 | LMNA (0.51) | LMNASMN1; SMN2TSHRMAPK1CYP2C19 | |
| SCHEMBL9659222 | 0.82 | LMNA (0.60) | LMNASMN1; SMN2BRD4TSHRMAPK1 | |
| SCHEMBL30881050 | 0.82 | LMNA (0.60) | LMNASMN1; SMN2BRD4TSHRMAPK1 | |
| SCHEMBL11700573 | 0.81 | LMNA (0.58) | LMNASMN1; SMN2TSHRMAPK1KMT2A | |
| SCHEMBL11694130 | 0.81 | LMNA (0.52) | LMNASMN1; SMN2TSHRMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132731-A | X-RAY CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | claimed |
| US-4132731-A | X-RAY CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |