Ioxitalamic Acid

Ioxitalamic Acid

SCHEMBL455411

CC(=O)Nc1c(I)c(C(=O)O)c(I)c(C(=O)NCCO)c1I

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.57
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 1/20 0.36
BRD4 O60885 1/20 0.34
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
MAP2K2 P36507 1/20 0.31
MAP2K1 Q02750 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ioxitalamic Acid SCHEMBL29815239 1.00 LMNA (0.57) LMNASMN1; SMN2GAABRD4CYP2C19
SCHEMBL11522720 0.92 LMNA (0.55) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL11775063 0.91 LMNA (0.51) LMNASMN1; SMN2GAACYP2C19HIF1A
SCHEMBL11178469 0.86 ALDH1A1 (0.36) LMNASMN1; SMN2CYP2C19HIF1AMAP2K2
SCHEMBL9395608 0.85 LMNA (0.46) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL30881050 0.85 LMNA (0.60) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL9659222 0.85 LMNA (0.60) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL11412072 0.85 LMNA (0.41) LMNASMN1; SMN2TSHRMAPK1
Ioxitalamic Acid SCHEMBL29730019 0.84 SMN1; SMN2 (0.78) LMNASMN1; SMN2GAACYP2C19HIF1A
SCHEMBL8610004 0.84 LMNA (0.40) LMNASMN1; SMN2TSHRMAPK1MAP2K2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683579-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC Yeung, Jeffrey E. (US) 2026-01-28 EP claimed
WO-2024158529-A1 RELIEVE BACK PAIN AND/OR REBUILDING INTERVERTERAL DISC YEUNG JEFFREY E (US) 2024-08-02 WO claimed
WO-2021238893-A1 EFFICIENT AND EFFECTIVE TISSUE CLEARING AGENTS AND THEIR COMPOSITIONS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2021-12-02 WO claimed
US-20210069352-A1 IODINE-BASED PARTICLES NANOPROBES, INC. 2021-03-11 US claimed
WO-2017165841-A1 IODINE-BASED PARTICLES NANOPROBES, INC. (US) 2017-09-28 WO claimed
US-20170274101-A1 IODINE-BASED PARTICLES NANOPROBES, INC. 2017-09-28 US claimed
US-20160375234-A1 TRANSPAPILLARY METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING BREAST CONDITIONS ATOSSA THERAPEUTICS, INC. 2016-12-29 US claimed
EP-3092027-A1 TRANSPAPILLARY METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING BREAST CONDITIONS Atossa Genetics Inc. (US) 2016-11-16 EP claimed
US-9393325-B2 Bioabsorbable co-filler for cerebrovascular aneurysms ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2016-07-19 US claimed
US-20160151124-A1 IMPLANTABLE MARKERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2016-06-02 US claimed
US-5330739-A Iodinated benzoyl acetals and ketals for x-ray imaging STERLING WINTHROP INC. (US) 1994-07-19 US claimed
US-5328404-A Contrast agents STERLING WINTHROP INC. (US) 1994-07-12 US claimed
EP-0603922-A1 Iodinated aroyloxy esters and their use as contrast agents in X-ray imaging NanoSystems L.L.C. (US) 1994-06-29 EP claimed
EP-0603917-A1 Iodinated agents and X-ray imaging compositions containing them NanoSystems L.L.C. (US) 1994-06-29 EP claimed
EP-0603923-A1 Iodinated aromatic acid derivatives and their use as contrast agents in X-ray imaging NanoSystems L.L.C. (US) 1994-06-29 EP claimed
EP-0601616-A1 Iodinated aroyloxy carboxamides and contrast agents containing them NanoSystems L.L.C. (US) 1994-06-15 EP claimed
EP-0601617-A1 Iodinated benzoyl acetals and ketals, and contrast agents containing them NanoSystems L.L.C. (US) 1994-06-15 EP claimed
US-5264610-A X-ray contrast agents STERLING WINTHROP INC. (US) 1993-11-23 US claimed
US-5260478-A Contrast agents in x-ray imaging compositions; medical diagnosis STERLING WINTHROP INC. (US) 1993-11-09 US claimed
WO-1980001244-A1 X-RAY CONTRAST MEDIA SOLUTIONS BYKGULDEN LOMBERG CHEM FAB (DE) 1980-06-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170274101-A1 IODINE-BASED PARTICLES TPO, BRI3BP, INSRR LMNA 3921/4885SMN1; SMN2 4574/4885GAA 2551/4885
US-20210069352-A1 IODINE-BASED PARTICLES TPO, BRI3BP, INSRR LMNA 3921/4885SMN1; SMN2 4574/4885GAA 2551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.