Ioxitalamic Acid

Ioxitalamic Acid

SCHEMBL29815239

CC(=O)Nc1c(I)c(C(=O)O)c(I)c(C(=O)NCCO)c1I

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.57
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 1/20 0.36
BRD4 O60885 1/20 0.34
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
MAP2K2 P36507 1/20 0.31
MAP2K1 Q02750 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ioxitalamic Acid SCHEMBL455411 1.00 LMNA (0.57) LMNASMN1; SMN2GAABRD4CYP2C19
SCHEMBL11522720 0.92 LMNA (0.55) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL11775063 0.91 LMNA (0.51) LMNASMN1; SMN2GAACYP2C19HIF1A
SCHEMBL11178469 0.86 ALDH1A1 (0.36) LMNASMN1; SMN2CYP2C19HIF1AMAP2K2
SCHEMBL9395608 0.85 LMNA (0.46) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL30881050 0.85 LMNA (0.60) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL9659222 0.85 LMNA (0.60) LMNASMN1; SMN2BRD4CYP2C19HIF1A
SCHEMBL11412072 0.85 LMNA (0.41) LMNASMN1; SMN2TSHRMAPK1
Ioxitalamic Acid SCHEMBL29730019 0.84 SMN1; SMN2 (0.78) LMNASMN1; SMN2GAACYP2C19HIF1A
SCHEMBL8610004 0.84 LMNA (0.40) LMNASMN1; SMN2TSHRMAPK1MAP2K2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616681-B2 Compositions and methods for treating renal injury CASE WESTERN RESERVE UNIVERSITY (US) 2026-05-05 US claimed
EP-3741381-B1 A PEPTIDE FOR USE FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY UNIV CORNELL (US) 2024-04-24 EP claimed
US-20230398172-A1 METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY CORNELL UNIVERSITY (US) 2023-12-14 US claimed
US-11628198-B2 Methods for prevention and treatment of acute renal injury CORNELL UNIVERSITY (US) 2023-04-18 US claimed
US-20230052363-A1 COMPOSITIONS AND METHODS FOR TREATING RENAL INJURY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-02-16 US claimed
US-12616681-B2 Compositions and methods for treating renal injury CASE WESTERN RESERVE UNIVERSITY (US) 2026-05-05 US disclosed
WO-2026090048-A1 RADIOPAQUE SHAPE MEMORY FOAM DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO disclosed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 US disclosed
EP-3484485-B1 COMPOSTIONS COMPRISING POLOXAMER FOR USE IN THE TREATMENT OF FISTULAE CENTRE NAT RECH SCIENT (FR) 2026-04-29 EP disclosed
US-20260108250-A1 RADIOPAQUE SHAPE MEMORY FOAM DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US disclosed
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-19 US disclosed
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-12 US disclosed
US-11931339-B2 Compositions and methods for treating tissue injury CASE WESTERN RESERVE UNIVERSITY (US) 2024-03-19 US disclosed
US-20240024297-A1 COMPOSITIONS AND METHODS FOR TREATING RENAL INJURY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-01-25 US disclosed
US-20230398172-A1 METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY CORNELL UNIVERSITY (US) 2023-12-14 US disclosed
US-11628198-B2 Methods for prevention and treatment of acute renal injury CORNELL UNIVERSITY (US) 2023-04-18 US disclosed
US-20230052363-A1 COMPOSITIONS AND METHODS FOR TREATING RENAL INJURY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-02-16 US disclosed
US-20230001128-A1 AEROSOLIZATION SYSTEMS, METHODS, AND APPARATUSES SHUSTER GARY STEPHEN (CA) 2023-01-05 US disclosed
EP-4106748-A1 COMPOSITIONS AND METHODS FOR TREATING RENAL INJURY CASE WESTERN RESERVE UNIVERSITY (US) 2022-12-28 EP disclosed
US-11389470-B2 Compositions useful for mucosal healing CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11628198-B2 Methods for prevention and treatment of acute renal injury ARG2, SERPINC1, ARG1 LMNA 2196/4885SMN1; SMN2 4340/4885GAA 2381/4885
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL LMNA 2822/4885SMN1; SMN2 3766/4885GAA 3244/4885
US-20230398172-A1 METHODS FOR PREVENTION AND TREATMENT OF ACUTE RENAL INJURY ARG2, SERPINC1, ARG1 LMNA 2196/4885SMN1; SMN2 4340/4885GAA 2381/4885
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM NPPA, MACF1, IGF1R LMNA 3574/4885SMN1; SMN2 3009/4885GAA 4766/4885
US-20230052363-A1 COMPOSITIONS AND METHODS FOR TREATING RENAL INJURY GLS, REN, PTGS1 LMNA 1018/4885SMN1; SMN2 3853/4885GAA 985/4885
US-11931339-B2 Compositions and methods for treating tissue injury PDK4, AK1, PDK1 LMNA 1588/4885SMN1; SMN2 2878/4885GAA 2160/4885
US-12616681-B2 Compositions and methods for treating renal injury PTGIS, PTGS1, PTGS2 LMNA 2413/4885SMN1; SMN2 4794/4885GAA 3567/4885
US-20240024297-A1 COMPOSITIONS AND METHODS FOR TREATING RENAL INJURY PTGS1, GLS, PTGS2 LMNA 2612/4885SMN1; SMN2 4231/4885GAA 1418/4885
US-11389470-B2 Compositions useful for mucosal healing MUC1, PGF, CD68 LMNA 3296/4885SMN1; SMN2 4364/4885GAA 3170/4885
US-20260041799-A1 HYDROLYSIS-RESISTANT HYDROGELS AND METHODS OF TREATMENT USING SAME PAM, CRYAA, COL1A1 LMNA 362/4885SMN1; SMN2 1218/4885GAA 958/4885
US-20260108250-A1 RADIOPAQUE SHAPE MEMORY FOAM DEVICES NPPA, CD47, PLAT LMNA 198/4885SMN1; SMN2 2218/4885GAA 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.