Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113750 | 0.84 | KDM4E (0.43) | BRD4ALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL115058 | 0.80 | ERCC1 (0.37) | BRD4ALDH1A1LMNASMN1; SMN2KCNA3 | |
| SCHEMBL115043 | 0.80 | ERCC1 (0.39) | BRD4ALDH1A1KCNA3TACR1KDM4E | |
| SCHEMBL116024 | 0.80 | METAP2 (0.39) | BRD4ALDH1A1TACR1KDM4EERCC1 | |
| SCHEMBL115090 | 0.78 | EGLN1 (0.45) | BRD4KMT2ALMNASMN1; SMN2KCNA3 | |
| SCHEMBL115067 | 0.76 | BRD4 (0.40) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL116163 | 0.75 | BRD4 (0.38) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL115089 | 0.73 | KCNA3 (0.44) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL115214 | 0.73 | BRD4 (0.42) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL115231 | 0.72 | F7 (0.44) | BRD4ALDH1A1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | BRD4 3524/4885ALDH1A1 274/4885KMT2A 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.